Frequently Asked Questions
What is the QCovid® score?
The QCovid® score is a risk score given by an evidence-based model
which uses a range of factors such as age, sex, ethnicity and existing
medical conditions to predict risk of death or hospitalisation from COVID-19.
It provides nuanced information on patient's risk of serious illness
due to COVID-19 and has the potential to help patients and doctors reach
a shared understanding of risk.
It is a 'living' risk prediction model will be updated regularly as our
understanding of COVID-19 increases and more data become available.
Why has it been developed?
QCovid® has been produced to provide doctors and the public with
more nuanced information about risk of serious illness due to COVID-19,
and to help patients and doctors reach a shared understanding of risk,
within the context of individual circumstances, risk attitude and the
sorts of preventative measures people can take in their daily lives.
Approximately 2.2 million people with pre-existing medical conditions
thought to be the most serious, such as organ transplant recipients
and people with severe respiratory conditions, were deemed 'clinically
extremely vulnerable' during the first wave of the COVID-19 pandemic in
England. These individuals were advised to shield themselves from the
virus by staying at home.
Throughout the pandemic, new information has emerged about what factors
may influence whether someone is seriously affected by COVID-19, creating
an opportunity to develop this detailed QCovid® risk prediction model.
Who developed it?
The research team is led by
Professor Julia Hippisley-Cox
at the University of Oxford and includes researchers from the universities of Cambridge,
Edinburgh, Swansea, Leicester, Nottingham and Liverpool with the London
School of Hygiene & Tropical Medicine, Queen's University Belfast,
Queen Mary University of London, University College London, the Department
of Health and Social Care, NHS Digital and NHS England.
How has it been developed?
QCovid® has been developed using the University of Oxford hosted
which has anonymised data from primary care, hospitals, COVID-19 test
results and death registries. This was used to determine which factors were
associated with poor outcomes during the first wave of COVID-19 and create a
risk prediction model - QCovid® - that provides a weighted, cumulative
calculation of absolute risk using the variables associated with poor COVID-19
outcomes. The factors incorporated in the model include age, ethnicity, level
of deprivation, obesity, whether someone lived in residential care or was homeless,
and a range of existing medical conditions, such as cardiovascular disease,
diabetes, respiratory disease and cancer.
This model was then tested in two independent sets of data, one from January
to April 2020 and one from May 2020 to June 2020, to find out whether it
accurately predicted severe outcomes due to COVID-19 during the first wave
of the pandemic in England.
published in the BMJ,
showed that the model performed well in
predicting severe outcomes due to COVID-19 (death and hospitalisation).
Who funded this research?
The research was funded by the NIHR following a commission by the Chief
Medical Officer for England. See press release
What does the absolute risk of a COVID-19 death mean and why is it important?
This is the risk of someone catching and then dying from COVID-19 over a 90-day
period. If someone has a risk of 2% then in a crowd of 100 people like them, on
average 2 people would catch and die from COVID-19 within 90 days. Or put another
way, they have a 'one in fifty chance of catching and dying from COVID-19 in the
next 90 days. If someone has a risk of 0.02% then in a crowd of 10,000 people like
them, on average 2 people would catch and die from COVID-19 within 90 days.
What is the relative risk measure?
The relative risk is the comparison between an individual's risk and the average
risk of a person of the same age and sex, a white ethnicity and body mass index
of 25 but without any risk factors such as medical conditions. It is a ratio of
the two risks, so if someone has a relative risk of 2 for COVID-19 death that means
their risk is twice as high as someone of the same age and sex as them but without
other risk factors. We compare against a person with White ethnicity in order to
highlight the differences in risk between ethnicities, rather than comparing individuals
within their own ethnic group.
Ranking a person’s risk
A rank is often a helpful measure alongside absolute risk. If we put the whole population
in a line, ranked according to their risk of death, and then divide this line into 100
equally sized groups, the person's score places them into a particular group.
Their rank is the group into which they fall.
Please note that ranks are not percentages. They show where the person is in the line
if we put everyone in order of risk, with 100, at the top, being the most at risk.
Which people can have a QCovid® score calculated?
The calculator can be used for people aged between 19 and 100 years.
What is the Townsend score, what does it measure and why was it used?
COVID-19 risk is associated with socio-economic status such that people from deprived
areas have higher risks. The use of equations that do not include a measure of
socio-economic status may exacerbate health inequalities, i.e. the difference
between rich and poor.
The Townsend score is a measure of material deprivation based on the area where
a person lives and obtained using their postcode. It includes four variables
obtained from census data: unemployment (lack of material resources and insecurity),
overcrowding (material living conditions), lack of owner-occupied accommodation
(a proxy indicator of wealth) and lack of car ownership (a proxy indicator of income).
This score is considered the best indicator of material deprivation currently
available and has been widely used in medical research including a range of
studies conducted on the QResearch database.
What is body mass index and how is it measured?
Body mass index is a number calculated from a person's height and weight. It is their
weight in kilograms divided by their height in metres squared.
Conventionally a person is considered to be obese if they have a body mass index over 30 kg/m2.
Which immunosuppressants are included here?
These are medicines which fall within chapter 8.2 of the British National Formulary
for example see
Which chemotherapy drugs are in each categories A, B and C?
Please see Supplementary Box A of the
Note that Supplementary Box A can be found in the Data Supplement, which is accessible under Related Content on the BMJ website.